New Pill for Advanced Pancreatic Cancer

Who this is for

Next clinical step

The US Food and Drug Administration (FDA) has approved this medicine. In the United States, ask your doctor or a specialist whether it suits you. They can write a prescription. Insurance or public drug plan coverage is not guaranteed. In Canada, authorisation is not confirmed; see Possible routes below if any are listed.

Ways to access this treatment

• United States · Prescription

  US prescription (FDA-labelled)

  https://www.fda.gov/news-events/press-announcements/fda-approves-first-class-targeted-therapy-metastatic-pancreatic-cancer

• Canada · Recruiting clinical trial

  Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  Combination or different setting. First-line daraxonrasib alone or with gemcitabine/nab-paclitaxel; the label is after prior therapy (phase 3).

  https://clinicaltrials.gov/study/NCT07491445

• United States · Recruiting clinical trial

  Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

  Combination or different setting. Adjuvant daraxonrasib after surgery for resected PDAC (phase 3).

  https://clinicaltrials.gov/study/NCT07252232

• United States · Recruiting clinical trial

  Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

  Combination or different setting. Tests daraxonrasib combined with zoldonrasib, first line (phase 3).

  https://clinicaltrials.gov/study/NCT07805954

Search all trials on ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=pancreatic%20cancer&intr=daraxonrasib&aggFilters=status:rec

Search Health Canada's Clinical Trials Search Portal: https://clinical-trials-search.canada.ca/en/search?search_api_fulltext=daraxonrasib

Possible routes (not confirmed)

• Canada · Health Canada Special Access Programme (SAP) · Applicability unknown

  Health Canada Special Access Programme (manufacturer must agree)

  SAP here depends on the manufacturer agreeing to supply; no confirmation for this drug.

  https://www.canada.ca/en/health-canada/services/drugs-health-products/special-access/drugs.html

General resources for further research

• Canadian Cancer Trials Group

  A national network conducting clinical trials for cancer treatment. Patients can search for trials by cancer type and location.

  https://www.ctg.queensu.ca/

• Canadian Clinical Trial Search Portal (Health Canada)

  Health Canada's public search of the drug and biologic clinical trials it has authorised in Canada (phase 1 to 3, since April 2013). Search by condition, drug, or trial status and see where trials are running. It replaced the Health Canada Clinical Trials Database in July 2026. A listing is not enrolment, and Health Canada does not recruit patients: ask your clinician and contact the trial sponsor.

  https://clinical-trials-search.canada.ca/en/home

• ClinicalTrials.gov

  US National Library of Medicine registry of clinical studies. Search by condition, drug, NCT number, and location. A listing is not enrolment, eligibility, or funding. Talk with the trial contact and a clinician before assuming a slot exists.

  https://clinicaltrials.gov/