New Daily Pill for Chronic Weight Management in Adults

Who this is for

Next clinical step

The US Food and Drug Administration (FDA) has approved this medicine. In the United States and the United Kingdom, ask your doctor or a specialist whether it suits you. They can write a prescription. Insurance or public drug plan coverage is not guaranteed. In Canada, authorisation is not confirmed; see Possible routes below if any are listed.

Ways to access this treatment

• United States · Prescription

  US prescription (FDA-labelled)

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8ac446c5-feba-474f-a103-23facb9b5c62

• United Kingdom · Prescription

  UK prescription (MHRA-authorised)

  https://www.gov.uk/government/news/uk-first-in-europe-to-authorise-orforglipron-for-weight-management-and-type-2-diabetes

• United States · Recruiting clinical trial

  A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  Tests this treatment. Orforglipron in adults with overweight at risk of complications (phase 3).

  https://clinicaltrials.gov/study/NCT07794579

• United States, Canada · Recruiting clinical trial

  A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

  Combination or different setting. Tests orforglipron for stress urinary incontinence in women with obesity (phase 3).

  https://clinicaltrials.gov/study/NCT07202884

• United States, United Kingdom · Recruiting clinical trial

  A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  Combination or different setting. Children 6-17 with obesity; the label is adults (phase 3).

  https://clinicaltrials.gov/study/NCT06672549

Search all trials on ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=obesity&intr=orforglipron&aggFilters=status:rec

Search Health Canada's Clinical Trials Search Portal: https://clinical-trials-search.canada.ca/en/search?search_api_fulltext=orforglipron

Possible routes (not confirmed)

• Canada · Health Canada Special Access Programme (SAP) · Applicability unknown

  Health Canada Special Access Programme (manufacturer must agree)

  SAP here depends on the manufacturer agreeing to supply; no confirmation for this drug.

  https://www.canada.ca/en/health-canada/services/drugs-health-products/special-access/drugs.html

General resources for further research

• Canadian Clinical Trial Search Portal (Health Canada)

  Health Canada's public search of the drug and biologic clinical trials it has authorised in Canada (phase 1 to 3, since April 2013). Search by condition, drug, or trial status and see where trials are running. It replaced the Health Canada Clinical Trials Database in July 2026. A listing is not enrolment, and Health Canada does not recruit patients: ask your clinician and contact the trial sponsor.

  https://clinical-trials-search.canada.ca/en/home

• ClinicalTrials.gov

  US National Library of Medicine registry of clinical studies. Search by condition, drug, NCT number, and location. A listing is not enrolment, eligibility, or funding. Talk with the trial contact and a clinician before assuming a slot exists.

  https://clinicaltrials.gov/