Once-Weekly Insulin Shot for Adults with Type 2 Diabetes

Who this is for

Next clinical step

Health Canada and the US Food and Drug Administration (FDA) have approved this medicine. In Canada, the United States, Australia and the European Union, ask your doctor or a specialist whether it suits you. They can write a prescription. Insurance or public drug plan coverage is not guaranteed. In Japan, China and Switzerland, authorisation is not confirmed; see Possible routes below if any are listed.

Ways to access this treatment

• United States · Prescription

  US prescription (FDA-labelled)

  https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/761326Orig2s000lbl.pdf

• Canada · Prescription

  Canada prescription (Health Canada NOC, DIN 02546205/02546213/02546221)

  https://health-products.canada.ca/api/drug/drugproduct/?din=02546205

• European Union · Prescription

  EU prescription (EC marketing authorisation)

  https://www.ema.europa.eu/en/medicines/human/EPAR/awiqli

• Australia · Prescription

  Australia prescription (ARTG-registered)

  https://www.tga.gov.au/resources/auspmd/awiqli-insulin-icodec

• European Union, Canada · Recruiting clinical trial

  A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes

  Tests this treatment. Insulin icodec vs daily basal insulin in type 2 diabetes (phase 4).

  https://clinicaltrials.gov/study/NCT07112339

• China · Recruiting clinical trial

  A Phase IIIb Clinical Study to Assess the Efficacy and Safety of GZR4 in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin

  Combination or different setting. Insulin icodec is the comparator arm; the trial tests GZR4.

  https://clinicaltrials.gov/study/NCT07165223

Search all trials on ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=type%202%20diabetes&intr=insulin%20icodec&aggFilters=status:rec

Search Health Canada's Clinical Trials Search Portal: https://clinical-trials-search.canada.ca/en/search?search_api_fulltext=insulin%20icodec

Possible routes (not confirmed)

• China · Not yet recruiting clinical trial · Applicability unknown

  Insulin Icodec Initiation Strategies and Day-4 Supplemental Dosing in Type 2 Diabetes

  Trial not yet recruiting (ClinicalTrials.gov status: not yet taking patients).

  https://clinicaltrials.gov/study/NCT07747402

General resources for further research

• Canadian Clinical Trial Search Portal (Health Canada)

  Health Canada's public search of the drug and biologic clinical trials it has authorised in Canada (phase 1 to 3, since April 2013). Search by condition, drug, or trial status and see where trials are running. It replaced the Health Canada Clinical Trials Database in July 2026. A listing is not enrolment, and Health Canada does not recruit patients: ask your clinician and contact the trial sponsor.

  https://clinical-trials-search.canada.ca/en/home

• ClinicalTrials.gov

  US National Library of Medicine registry of clinical studies. Search by condition, drug, NCT number, and location. A listing is not enrolment, eligibility, or funding. Talk with the trial contact and a clinician before assuming a slot exists.

  https://clinicaltrials.gov/

• Human Research Switzerland (HumRes) trial search

  Public Swiss clinical-trial search on Human Research Switzerland (HumRes). Search studies taking place in Switzerland. A listing is not Swissmedic authorisation and is not enrolment.

  https://www.humanforschung-schweiz.ch/en/trial-search/

• CTIS (EU Clinical Trials Information System)

  European Union public portal for clinical trials submitted under the Clinical Trials Regulation. Search by medicine, condition, and member state. A CTIS record is not an EMA marketing authorisation and is not enrolment.

  https://euclinicaltrials.eu/

• jRCT (Japan Registry of Clinical Trials)

  Japan Registry of Clinical Trials, the public registry used under Japanese clinical-trial rules. Search studies by condition and location. A jRCT listing is not PMDA approval and is not enrolment.

  https://jrct.mhlw.go.jp/en-top