New Pill When the Heart Muscle Is Too Thick

Who this is for

Next clinical step

Health Canada and the US Food and Drug Administration (FDA) have approved this medicine. In Canada, the United States, the United Kingdom, China and the European Union, ask your doctor or a specialist whether it suits you. They can write a prescription. Insurance or public drug plan coverage is not guaranteed. In Canada, it is authorised but may not be on sale yet.

Ways to access this treatment

• United States · Prescription

  US prescription (FDA-labelled)

  https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219083s000lbl.pdf

• United States · Prescription with safety programme (REMS)

  MYQORZO REMS (prescriber/pharmacy certification)

  https://www.myqorzorems.com

• United Kingdom · Prescription

  UK prescription (MHRA-authorised)

  https://www.gov.uk/government/news/thousands-of-patients-to-benefit-from-new-daily-pill-for-serious-heart-condition-following-co-ordinated-mhra-and-nice-decisions

• European Union · Prescription

  EU prescription (EC marketing authorisation)

  https://www.ema.europa.eu/en/medicines/human/EPAR/myqorzo

• China · Prescription

  China prescription (NMPA-approved, 国药准字 HJ20250147)

  https://www.sanofi.cn/assets/dot-cn/pages/docs/products/prescription-products/Aficamten_tab_LRL_PI-CN-20260811.pdf

• United States · Recruiting clinical trial

  Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy

  Combination or different setting. Tests switching to aficamten in adults already on mavacamten (phase 4).

  https://clinicaltrials.gov/study/NCT07600177

See 1 trial on ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=hypertrophic%20cardiomyopathy&intr=aficamten&aggFilters=status:rec

Possible routes (not confirmed)

• Canada · Prescription · Applicability unknown

  Canada prescription (Health Canada NOC 38476, DIN 02572702/02572710/02572729/02572737)

  Health Canada issued a Notice of Compliance (NOC) on 2026-10-14 (DIN 02572702/02572710/02572729/02572737), but the Drug Product Database does not list it as marketed yet; Canadian supply date not confirmed.

  https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=107464

General resources for further research

• Canadian Clinical Trial Search Portal (Health Canada)

  Health Canada's public search of the drug and biologic clinical trials it has authorised in Canada (phase 1 to 3, since April 2013). Search by condition, drug, or trial status and see where trials are running. It replaced the Health Canada Clinical Trials Database in July 2026. A listing is not enrolment, and Health Canada does not recruit patients: ask your clinician and contact the trial sponsor.

  https://clinical-trials-search.canada.ca/en/home

• ClinicalTrials.gov

  US National Library of Medicine registry of clinical studies. Search by condition, drug, NCT number, and location. A listing is not enrolment, eligibility, or funding. Talk with the trial contact and a clinician before assuming a slot exists.

  https://clinicaltrials.gov/

• CTIS (EU Clinical Trials Information System)

  European Union public portal for clinical trials submitted under the Clinical Trials Regulation. Search by medicine, condition, and member state. A CTIS record is not an EMA marketing authorisation and is not enrolment.

  https://euclinicaltrials.eu/